Insulin resistance impairs nigrostriatal dopamine function
نویسندگان
چکیده
منابع مشابه
Nigrostriatal Dopamine Function and Insulin Resistance by Jill
Clinical studies have indicated a link between Parkinson’s disease (PD) and Type 2 Diabetes. Although preclinical studies have examined the effect of high-fat feeding on dopamine function in brain reward pathways, the effect of diet on neurotransmission in the nigrostriatal pathway, which is affected in PD and parkinsonism, is less clear. We hypothesized that a high-fat diet, which models early...
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ژورنال
عنوان ژورنال: Experimental Neurology
سال: 2011
ISSN: 0014-4886
DOI: 10.1016/j.expneurol.2011.06.005